Automated classification of primary progressive aphasia subtypes from narrative speech transcripts

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Automated classification of primary progressive aphasia subtypes from narrative speech transcripts.

In the early stages of neurodegenerative disorders, individuals may exhibit a decline in language abilities that is difficult to quantify with standardized tests. Careful analysis of connected speech can provide valuable information about a patient's language capacities. To date, this type of analysis has been limited by its time-consuming nature. In this study, we present a method for evaluati...

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Degeneration of language regions in the dominant hemisphere can result in primary progressive aphasia (PPA), a clinical syndrome characterized by progressive deficits in speech and/or language function. Recent studies have identified three variants of PPA: progressive non-fluent aphasia (PNFA), semantic dementia (SD) and logopenic progressive aphasia (LPA). Each variant is associated with chara...

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Narrative speech can provide a valuable source of information about an individual’s linguistic abilities across lexical, syntactic, and pragmatic levels. However, analysis of narrative speech is typically done by hand, and is therefore extremely time-consuming. Use of automatic speech recognition (ASR) software could make this type of analysis more efficient and widely available. In this paper,...

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Connected speech production in three variants of primary progressive aphasia.

Primary progressive aphasia is a clinical syndrome defined by progressive deficits isolated to speech and/or language, and can be classified into non-fluent, semantic and logopenic variants based on motor speech, linguistic and cognitive features. The connected speech of patients with primary progressive aphasia has often been dichotomized simply as 'fluent' or 'non-fluent', however fluency is ...

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Primary progressive aphasia: from syndrome to disease.

INTRODUCTION Primary progressive aphasia (PPA) is a clinical syndrome characterised by a progressive decline in language and speech of neurodegenerative origin. Major breakthroughs made in recent years have lent us a better understanding of this syndrome, which may be the first manifestation of any of a number of neurodegenerative diseases. DEVELOPMENT We reviewed the main aspects of PPA epid...

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ژورنال

عنوان ژورنال: Cortex

سال: 2014

ISSN: 0010-9452

DOI: 10.1016/j.cortex.2012.12.006